You are cordially invited to attend the seminar organized by the Department of Chemistry.
Title: High resolution syringe-injectable brain-computer interfaces
Speaker: Dr. Emre Mulazimoglu
Date: 13/01/2026, Tuesday
Time: 12:30 (Turkiye Time)
Place: SBZ-14
High resolution syringe-injectable brain-computer interfaces
A platform capable of linking sub-cellular electrophysiological signals to circuit-level modifications that unfold over years would fundamentally transform our understanding of how the brain functions in health and disease. Achieving this goal requires chronic, long-term stable, and minimally invasive interfaces that can record from and stimulate neural circuits with high spatial resolution—capabilities that remain beyond current neurotechnologies. Conventional implantable probes suffer from limited temporal stability due to mechanical mismatch with soft brain tissue, preventing access to long-term processes such as learning, memory formation, and aging.
Mesh electronics, a syringe-injectable neural interface platform, overcomes many of these limitations by enabling seamless integration with brain tissue and stable recordings over extended periods. However, its spatial resolution is currently constrained by micron-scale metal electrodes that are comparable in size to the neurons they interrogate. In this seminar, I will present a nanoscience-based strategy to overcome this limitation by integrating active one-dimensional silicon nanowire field-effect transistors (SiNW-FETs) into mesh electronics as high-sensitivity sensors and actuators.
By combining the unique electronic properties of SiNW-FETs with the ultra-flexible, tissue-like architecture of mesh electronics, this platform enables long-term stable recording and stimulation of neural activity with sub-cellular spatial resolution and minimal invasiveness—capabilities not achievable with state-of-the-art approaches. Seamlessly interfacing nanoscience and neuroscience, this work establishes a scalable framework for decoding dynamic neural circuitry underlying learning, cognition, memory, and aging, while opening new opportunities for precision neuromodulation and personalized treatment strategies for neurological and neuropsychiatric disorders, including epilepsy and Alzheimer’s disease.
Short Biography of the Speaker: Dr. Emre Mulazimoglu completed his BSc & MScs degree at the Metallurgical and Materials Engineering Department, Middle East Technical University (METU). His MSc research focused on synthesis and utilization of Silicon nanowires in optoelectronic devices. Following his MSc studies, He moved to The Netherlands for his PhD degree in applied physics at the Kavli Institute of Nanoscience. During his PhD, he investigated superconducting oxide interfaces using nanoscale devices. His work created the first superconducting quantum interference devices at the oxide interfaces and later demonstrated for the first-time superconducting quantum point contact devices using nanoscale gates, both realizing superconducting devices with electrostatic interfaces. This created a new research direction in the field of both complex oxides and superconducting circuit elements. Next, he worked as a postdoctoral research fellow first at Harvard University and then University of Twente. At Harvard University, he developed a new platform, high resolution syringe injectable brain-computer interfaces, for in-vivo neuroscience under the supervision of Prof. Charles M. Lieber. He has (co)-authored 8 papers in international peer-reviewed journals containing high impact scientific journals (among others: Nature Nanotechnology, Nature Communications, Physical Review Letters, Nano Letters).