Dear Colleagues and Students,<\/p>\n
You are cordially invited to UNAM Nanocolloquium seminars focusing on advancements in the field of nanoscience and nanotechnology. The seminars bring us the most recent developments in these exciting fields.<\/p>\n
The second talk of this spring term will be presented by Prof. Raffaele Mezzenga*<\/p>\n
Title: Nanotechnology and Materials Science using Protein Nanofibrils
\nDate: February 9, 2017 (Friday)
\nTime: 16:00**
\nPlace: UNAM Conference Hall<\/p>\n
ABSTRACT –
\nProtein fibrils are protein aggregates, which can be generated from food-grade proteins by unfolding and hydrolysis. Differently from the pathological homologue amyloid fibrils, which form in vivo from toxic protein and peptides, the resulting protein fibrils formed from food protein precursors can be used in a broad context of applications. At length scales above the well-established atomistic fingerprint of amyloid fibrils, these colloidal aggregates exhibit mesoscopic properties comparable to those of natural polyelectrolytes, yet with persistence lengths several orders of magnitude beyond the Debye length. This intrinsic rigidity, together with their chiral, polar and charged nature, provides these systems with some unique physical behavior. In this talk I will discuss our current understanding on the mesoscopic properties of amyloid fibrils at the single molecule level, the implication of their semiflexible nature on their liquid crystalline properties, and I will illustrate how this information prove useful in understanding their collective behavior in bulk and when adsorbed at liquid interfaces. By the careful exploitation of the physical properties of amyloid fibrils, the design of advanced materials with unprecedented physical properties become possible, and I will give a few examples on how these systems can ideally suit the design of biosensors and biomaterials, cellular scaffolds, biomoimetic bones, catalytic and water purification membranes. In the end of the talk I will emphasize how the non-toxic nature of the protein fibrils considered allow original applications in food science and nutrition, by providing unchallenged delivery systems for nanostructured bioavailable iron. 1.\u201cUnderstanding amyloid aggregation by statistical analysis of atomic force microscopy images\u201d Adamcik et al., Nature nanotechnology, 5, 423 (2010). 2. \u201cBiodegradable Nanocomposites of Amyloid Fibrils and Graphene with Shape Memory and Enzyme Sensing Properties\u201d Li et al. Nature nanotechnology, 7, 421 (2012). 3. \u201cAmyloid\u2013carbon hybrid membranes for universal water purification\u201d Bolisetty et al. Nature nanotechnology, 11, 365 (2016). 4. \u201cAmyloid fibril systems reduce, stabilize and deliver bioavailable nanosized iron\u201d Shen et al. Nature nanotechnology, 12, 642 (2017).<\/p>\n
About the Speaker:
\nRaffaele Mezzenga received his master degree (Summa Cum Laude) from Perugia University, Italy, in Materials Science and Engineering, while actively working for the European Center for Nuclear Research (CERN) and NASA on elementary particle-polymer interactions (NASA Space Shuttle Discovery mission STS91). In 2001 he obtained a PhD in Polymer Physics from EPFL Lausanne, focusing on the thermodynamics of reactive polymer blends. He then spent 2001-2002 as a postdoctoral scientist at University of California, Santa Barbara, working on the self-assembly of polymer colloids. In 2003 he moved to the Nestl\u00e9 Research Center in Lausanne as research scientist, working on the self-assembly of surfactants, natural amphiphiles and lyotropic liquid crystals. In 2005 he was hired as Associate Professor in the Physics Department of the University of Fribourg, and he then joined ETH Zurich on 2009 as Full Professor. In 2016 he founded BluAct Technologies, an ETH Spinoff exploiting a revolutionary technology for water purification, where he currently serves as Chief Scientific Officer. His research focuses on the fundamental understanding of self-assembly processes in polymers, lyotropic liquid crystals, food and biological colloidal systems. Prof. Mezzenga has been a visiting Professor from Helsinki University of Technology (now Aalto University), a Nestl\u00e9 Distinguished Scientist, and recipient of several international distinctions such as the 2011 John H. Dillon Medal and the 2017 Fellowship of the American Physical Society [citation: \u201cFor exceptional contributions to the understanding of self-assembly principles and their use to design and control materials with targeted functionalities\u201c], the 2011 AOCS Young Scientist Research Award [citation: \u201cFor his pioneering work on polymers, colloids and liquid crystals\u201c], and the 2013 the Biomacromolecules\/Macromolecules 2013 Young Investigator Award of the American Chemical Society [citation: \u201cIn recognition of his outstanding contributions to the fundamental understanding of self-assembly processes in polymers and biological colloidal systems\u201d]\n
*ETH Z\u00fcrich<\/p>\n
** Refreshment will be served at 15:40<\/p>\n","protected":false},"excerpt":{"rendered":"
Dear Colleagues and Students, You are cordially invited to UNAM Nanocolloquium seminars focusing on advancements in the field of nanoscience and nanotechnology. The seminars bring us the most recent developments in these exciting fields. The second talk of this spring term will be presented by Prof. Raffaele Mezzenga* Title: Nanotechnology [\u2026] <\/p>\n