Alkan Kabak\u00e7\u0131o\u011flu
\nKo\u00e7 University<\/p>\n
\u201cOut-of-equilibrium dynamics in biology and machine learning\u201d<\/p>\n
Abstract
\nDynamical trajectories in high-dimensional systems can exhibit complex and sometimes counterintuitive behaviors driven by noise. We here provide two examples: one from biology, involving the folding and melting dynamics of nucleic acids under thermal drive, and another from machine learning, where the training process can be seen as evolution under nonthermal noise in a complex loss landscape. In the first case, we demonstrate the time-reversal asymmetry between the folding and melting processes and find a type of Mpemba effect in the melting dynamics of the RNA hairpin, both underlining the importance of the molecule\u2019s helical ground state in its nonequilibrium response to thermal effects. In the second case, the show how the nontrivial correlations in the gradient noise induced by minibatching result in a non-Boltzmanian stationary state with finite angular momentum and entropy production which, nonetheless, are in excellent agreement with detailed and integral fluctuation theorems.<\/p>\n
Alkan Kabak\u00e7\u0131o\u011flu is an Assistant Professor of Physics at Ko\u00e7 University. His research focuses on statistical mechanics and its applications to biological systems and complex networks. He previously held postdoctoral positions at the Weizmann Institute of Science and the University of Padova. He received his Ph.D. in Physics from MIT, and holds M.Sc. and B.Sc. degrees from Bilkent University.<\/p>\n
Date: 26 November 2025, Wednesday
\nTime: 15:30
\nPlace: SA-240<\/p>\n
All interested are cordially invited.<\/p>\n","protected":false},"excerpt":{"rendered":"
Alkan Kabak\u00e7\u0131o\u011flu Ko\u00e7 University \u201cOut-of-equilibrium dynamics in biology and machine learning\u201d Abstract Dynamical trajectories in high-dimensional systems can exhibit complex and sometimes counterintuitive behaviors driven by noise. We here provide two examples: one from biology, involving the folding and melting dynamics of nucleic acids under thermal drive, and another from [\u2026] <\/p>\n